6 results for "Retinoid X Receptor Agonists Small Molecules and Peptides" in 产品
Retinoid X Receptor Agonists Small Molecules and Peptides
Retinoid X receptors (RXR) are members of the NR2B family of nuclear receptors and are common binding partners to many other nuclear receptors, including PPARs, liver X receptors (LXRs) and vitamin D receptors (VDR). RXR heterodimers act as ligand-dependent transcriptional regulators and increase the DNA-binding efficiency of its partner.
Despite numerous studies, the physiological role of RXRs have yet to been fully elucidated and, as they can also exist as homodimers, there is the possibility ...
Endogenous retinoic acid receptor agonist
| Alternate Names: | Tretinoin,ATRA |
| Chemical Name: | 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid |
| Purity: | ≥98% |
Pan RXR agonist
| Alternate Names: | BMS 649 |
| Chemical Name: | 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoic acid |
| Purity: | ≥98% |
Potent and selective RXRα agonist
| Chemical Name: | 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid |
| Purity: | ≥97% |
Potent and selective RXR agonist
| Alternate Names: | LGD 1069 |
| Chemical Name: | 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid |
| Purity: | ≥98% |
RXR agonist
| Alternate Names: | DHA |
| Chemical Name: | (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid |
| Purity: | ≥98% |
Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers
| Chemical Name: | 6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic acid |
| Purity: | ≥98% |
