6 results for "LXR-like Receptor Agonists" in Products
LXR-like Receptor Agonists
Liver X receptors (LXRs) and farnesoid X receptors (FXRs) are members of the steroid analog-activated nuclear receptor subfamily, which form heterodimers with members of the retinoid X receptor family. There are two closely related isoforms of each of these enzymes; LXRα and LXRβ, and FXRα and FXRβ (pseudogene in man).
LXRα and FXRα expression is restricted to the liver, small intestine, kidney and adrenal gland, whilst LXRβ and FXRβ are ubiquitously ...
Selective farnesoid X receptor (FXR) agonist
| Chemical Name: | 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid |
| Purity: | ≥97% |
Potent liver X receptor (LXR) agonist; also CAR inverse agonist
| Chemical Name: | N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide |
| Purity: | ≥98% |
Orally active liver X receptor (LXR) agonist
| Chemical Name: | 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride |
| Purity: | ≥98% |
Potent, selective farnesoid X receptor (FXR) agonist
| Chemical Name: | 3-[3-[(Cyclohexylcarbonyl)-[[4'-(dimethylamino)-[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoic acid methyl ester |
| Purity: | ≥97% |
LXR agonist; also ER partial agonist
| Alternate Names: | 27 OHC,27 HC |
| Chemical Name: | (3β,25R)-Cholest-5-ene-3,26-diol |
| Purity: | ≥95% |
Potent LXR agonist
| Chemical Name: | 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole |
| Purity: | ≥98% |
