7 results for "RIP Kinase Inhibitors" in 产品
RIP Kinase Inhibitors
RIPK1 (Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1), also known as RIP1, contains an N-terminal protein kinase domain, a C-terminal death domain, and a unique internal region called the intermediate domain. It is a serine/threonine protein kinase and is constitutively expressed in many tissues. RIPK1 interacts with the cytoplasmic death...
Potent RIPK2 inhibitor
| Chemical Name: | 3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide |
| Purity: | ≥98% |
RIP1 kinase inhibitor; inhibits necroptosis
| Chemical Name: | 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone |
| Purity: | ≥98% |
Potent and metabolically stable RIP1 kinase inhibitor
| Chemical Name: | N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide |
| Purity: | ≥98% |
Potent RIPK2 inhibitor; orally bioavailable and cell permeable
| Chemical Name: | 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine |
| Purity: | ≥98% |
Potent and selective RIP3 kinase inhibitor
| Chemical Name: | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Purity: | ≥98% |
Potent and selective RIPK3 inhibitor; also blocks activation of necroptosis
| Chemical Name: | 3-(3-Hydroxyphenyl)-1-methyl-7-[[3-(4-methyl-1-piperazinyl)phenyl]amino]-1,6-naphthyridin-2(1H)-one dihydrochloride |
| Purity: | ≥98% |
RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant
| Chemical Name: | N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide |
| Purity: | ≥98% |
