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154 results for "ROCK1" in 产品
ROCK1 Products
Rho-associated kinase I (ROCK1, ROK beta, p160ROCK) is a serine-threonine protein kinase and an effector of the small GTPase Rho. With N-terminus protein kinase domain and C-terminus Rho-binding domain/pleckstrin homology domain, ROCK1 can be activated by either RhoA or RhoB. In Rho specific ROCK1 activation, a Rho protein binds to the Rho-binding domain and induces a conformational change which opens the kinase domain for the phosphorylation of downstream effectors (1). Activated ROCK1 ...
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TB1254-GMP
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| Alternate Names: | y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor |
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥99% |
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| Reactivity: | Human, Mouse, Rat, Canine, Primate, +1 More |
| Details: | Mouse IgG Monoclonal Clone #154C1465 |
| Applications: | WB, ICC/IF |
![Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)BSA Free [NB100-56596]](https://resources.rndsystems.com/images/products/cleaved-ROCK1-Antibody-154C1465-Western-Blot-NB100-56596-img0004.jpg "Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)BSA Free [NB100-56596]")
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| Chemical Name: | N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide |
| Purity: | ≥98% |
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| Chemical Name: | (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: ROCK1 Antibody [NB100-624]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-NB100-624-img0003.jpg "Western Blot: ROCK1 Antibody [NB100-624]")
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| Reactivity: | Human, Mouse, Rat, Canine, Primate, +1 More |
| Details: | Mouse IgG Monoclonal Clone #154C1465 |
| Applications: | WB, ICC/IF |
![Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)Azide Free [NBP2-33238]](https://resources.rndsystems.com/images/products/cleaved-ROCK1-Antibody-154C1465-Azide-Free-Western-Blot-NBP2-33238-img0001.jpg "Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)Azide Free [NBP2-33238]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #701118 |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Mycoplasma |
![Western Blot: ROCK1 Antibody [NBP1-82450]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-Western-Blot-NBP1-82450-img0008.jpg "Western Blot: ROCK1 Antibody [NBP1-82450]")
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| Alternate Names: | HA 1077 |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #261 |
| Applications: | WB |
![Western Blot: ROCK1 Antibody (261) [NBP2-42917]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-261-Western-Blot-NBP2-42917-img0005.jpg "Western Blot: ROCK1 Antibody (261) [NBP2-42917]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #464 |
| Applications: | WB |
![Western Blot: ROCK1 Antibody (464) [NBP2-42918]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-464-Western-Blot-NBP2-42918-img0004.jpg "Western Blot: ROCK1 Antibody (464) [NBP2-42918]")
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB |
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| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2E2 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: ROCK1 Antibody (2E2) [H00006093-M01]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-2E2-Western-Blot-H00006093-M01-img0008.jpg "Western Blot: ROCK1 Antibody (2E2) [H00006093-M01]")
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| Chemical Name: | N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]benzamide |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: ROCK1 AntibodyBSA Free [NBP1-76569]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-Western-Blot-NBP1-76569-img0001.jpg "Western Blot: ROCK1 AntibodyBSA Free [NBP1-76569]")
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| Reactivity: | Human |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005406 |
| Applications: | Bioactivity |
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| Chemical Name: | (S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | (3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride |
| Purity: | ≥98% |
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| Alternate Names: | Azaindole-1,BAY-549 |
| Chemical Name: | 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% |
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| Chemical Name: | N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | 2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea |
| Purity: | ≥98% |
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| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥97% |
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| Chemical Name: | (2R)-4-(3-Fluoro-4-pyridinyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]-2-methyl-1-piperazinecarboxamide |
| Purity: | ≥98% |
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