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2 results for "SCNN1D Small Molecules and Peptides" in 产品
SCNN1D Small Molecules and Peptides
SCNN1D is a subunit of the epithelial sodium channel (ENaC). ENaC has high sodium selectivity, low conductance, and amiloride sensitivity. The epithelial Na(+) channel (ENaC) regulates Na(+) homeostasis in cells and across epithelia; in the kidney, lung and colon it plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium re-uptake in the distal nephron of the kidney, thus regulating blood pressure. Four homologous ENaC subunits ...
TRPV antagonist; also activator of ENaCδ
| Chemical Name: | N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide |
| Purity: | ≥98% |
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NCX inhibitor, Deg/ENaC channel blocker; amiloride (Cat. No. 0890) derivative
| Chemical Name: | N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride |
| Purity: | ≥98% |
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