18 results for "secretase-inhibitors" in 产品

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)
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γ-secretase inhibitor; induces neuronal differentiation

Alternate Names: γ-Secretase Inhibitor XXI
Chemical Name: N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity: ≥98%
γ-secretase inhibitor; induces neuronal differentiation
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Potent and selective γ-secretase inhibitor

Alternate Names: L 458,γ-Secretase Inhibitor X
Chemical Name: (5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucy-L-phenylalaninamide
Purity: ≥97%
Potent and selective γ-secretase inhibitor
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DAPT synthesized to Ancillary Material Grade

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity: ≥99%
DAPT synthesized to Ancillary Material Grade
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γ-secretase inhibitor; inhibits Notch pathway

Alternate Names: Dibenzazepine,YO-01027
Chemical Name: N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity: ≥98%
γ-secretase inhibitor; inhibits Notch pathway
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Potent γ-secretase inhibitor

Chemical Name: (2S)-2-[[(2S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1H-imidazol-4-yl]pentanamide dihydrobromide
Purity: ≥98%
Potent γ-secretase inhibitor
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γ-secretase inhibitor; attenuates amyloid plaque deposition

Chemical Name: N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide
Purity: ≥98%
γ-secretase inhibitor; attenuates amyloid plaque deposition
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Potent γ-secretase inhibitor

Chemical Name: 2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid
Purity: ≥98%
Potent γ-secretase inhibitor
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Inhibitor of Aβ42 fibril formation

Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Purity: ≥98%
Inhibitor of Aβ42 fibril formation
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Potent and selective γ-secretase inhibitor; also induces differentiation of iEM cells into luminal cells

Alternate Names: RG-4733
Chemical Name: 2,2-Dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide
Purity: ≥98%
Potent and selective γ-secretase inhibitor; also induces differentiation of iEM cells into luminal cells
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