3 results for "STING-dependent Signaling Compounds Small Molecules and Peptides" in 产品

STING-dependent Signaling Compounds Small Molecules and Peptides

STING (stimulator of interferon genes) is a pattern recognition receptor and adapter protein that is anchored in the endoplasmic reticulum (ER), and is highly expressed in immune cells. STING-dependent signaling mediates a Toll-like receptor independent innate immune response following detection of cytoplasmic pathogens.

The invasion of a cell by a pathogen, such as a virus or bacterium, results in a host defence response mediated by the adapter protein STING. Foreign DNA is detected by ...

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Endogenous agonist at S1P1-5

Chemical Name: (E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Purity: ≥98%
Endogenous agonist at S1P1-5
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Blocker of VRAC/ICl, swell

Alternate Names: SN-401
Chemical Name: 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid
Purity: ≥98%
Blocker of VRAC/ICl, swell
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Induces expression of STING and STING-related genes; antiviral

Chemical Name: 3',2'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Purity: ≥98%
Induces expression of STING and STING-related genes; antiviral
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