7 results for "TRPM8 Small Molecules and Peptides" in 产品
TRPM8 Small Molecules and Peptides
TRPM8 functions as a cold receptor in sensory neurons but is also expressed in tissues not exposed to ambient temperatures, as well as in cancer tissues. TRPM8 is expressed in prostate and in most in prostate tumors. TRPM8 is also expressed in non-prostatic primary tumors such as colon, lung, breast and skin tumors. There are two shorter splice variants of TRPM8, termed short TRPM8a and short TRPM8ß. Both variants are in a closed configuration with the C-terminal tail of the full-length ...
TRPM8 agonist; cooling agent
| Chemical Name: | (1R*,2S*)-N-(4-Methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide |
| Purity: | ≥99% |
TRPM8 blocker
| Chemical Name: | N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride |
| Purity: | ≥98% |
TRPM8 blocker
| Chemical Name: | N-(4-Fluorophenyl)-3,4-dihydro-1-[4-(trifluoromethyl)phenyl]-2(1H)-isoquinolinecarboxamide |
| Purity: | ≥98% |
Potent and selective TRPM8 channel blocker
| Chemical Name: | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride |
| Purity: | ≥98% |
Potent TRPM8 antagonist
| Chemical Name: | 3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene |
| Purity: | ≥98% |
Potent and selective TRPM8 antagonist; active in vivo
| Chemical Name: | 6-[[[(S)-(3-Fluoro-2-pyridinyl)[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]-3-pyridinecarboxylic acid |
| Purity: | ≥98% |
Activates cold receptors. Cooling agent
| Alternate Names: | AG 3-5 |
| Chemical Name: | 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one |
| Purity: | ≥98% |
