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2 results for "Voltage-gated Calcium Channel Blockers" in 产品
Voltage-gated Calcium Channel Blockers
Voltage-gated calcium channels (CaV) are present in the membrane of most excitable cells and mediate calcium influx in response to depolarization. They regulate processes such as muscle contraction, secretion, neurotransmission and gene expression.
CaV channels are formed from four or five distinct subunits: α1, α2, δ, β and γ. The transmembrane α1-subunit, for which there are 10 genes, is the largest subunit and incorporates the voltage sensor, conduction pore ...
CaV3.x blocker
| Chemical Name: | 4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Purity: | ≥98% |
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CaV3.2 and CaV3.1 channel blocker; orally bioavailable
| Chemical Name: | 4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]carbonyl]benzenesulfonamide |
| Purity: | ≥98% |
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