1-Deazaadenosine

Key Product Details

Product Description

1-Deazaadenosine is an inhibitor of adenosine deaminase (K_i = 0.66 μM). Demonstrates antitumor activity in a range of leukemia cell lines.

Product Specifications for 1-Deazaadenosine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 1-Deazaadenosine

The following data is based on the product molecular weight 266.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	15.02 mL	75.12 mL	150.23 mL
1.25 mM	3.00 mL	15.02 mL	30.05 mL
2.5 mM	1.50 mL	7.51 mL	15.02 mL
12.5 mM	0.30 mL	1.50 mL	3.00 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Cristalli Improved synthesis and antitumor activity of 1-deazaadenosine. J.Med.Chem. 1987 PMID: 3625714
• Cristalli Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res.

Product Documents for 1-Deazaadenosine