Catalog Number: 1259
Chemical Name: (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride
Biological Activity
Selective inhibitor of α-mannosidase I.
Technical Data
  • M.Wt:
    199.63
  • Formula:
    C6H13NO4.HCl
  • Solubility:
    Soluble to 50 mM in water
  • Storage:
    Desiccate at RT
  • CAS No:
    73465-43-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells.
    Bischoff et al.
    J.Biol.Chem., 1986;261:4766
  2. The effect of 1-deoxymannojirimycin on rat liver α-mannosidases.
    Bischoff and Kornfeld
    Biochem.Biophys.Res.Commun., 1984;125:324
  3. Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides.
    Fuhrmann et al.
    Nature, 1984;307:755
Citations:

The citations listed below are publications that use Tocris products. Selected citations for 1-Deoxymannojirimycin hydrochloride include:

1 Citations: Showing 1 - 1

  1. Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells.
    Authors: Tareen Et al.
    Mol Ther 2014;22:575

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