1-Oleoyl lysophosphatidic acid sodium salt

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1-Oleoyl lysophosphatidic acid sodium salt | CAS No. 325465-93-8 | Lysophosphatidic Acid (LPA) Receptor Agonists
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Description: Endogenous agonist of LPA1 and LPA2

Chemical Name: 1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt

Product Details
Citations (10)
Supplemental Products

Biological Activity

1-Oleoyl lysophosphatidic acid sodium salt is an endogenous agonist of the lysophospholipid receptors LPA1 and LPA2. 1-Oleoyl lysophosphatidic acid sodium salt inhibits differentiation of neural stem cells (NSCs) into neurons.

Note: This product is typically prepared in PBS, pH 7.2, at a concentration of up to approximately 4 mg/mL.

Technical Data

Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for 1-Oleoyl lysophosphatidic acid sodium salt

The citations listed below are publications that use Tocris products. Selected citations for 1-Oleoyl lysophosphatidic acid sodium salt include:

10 Citations: Showing 1 - 10

  1. Generating human blastoids modeling blastocyst-stage embryos and implantation.
    Authors: Maria Et al.
    Nat Protoc  2023;18:1584-1620
  2. Human blastoids model blastocyst development and implantation.
    Authors: Maria Et al.
    Nature  2022;601:600-605
  3. Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells.
    Authors: Janet Et al.
    Cell Stem Cell  2022;29:1346-1365.e10
  4. Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction.
    Authors: Natarajan V Et al.
    Nat Cell Biol  2022;24:858-871
  5. A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression.
    Authors: Jop Et al.
    Development  2022;149
  6. Human embryos in a dish - modeling early embryonic development with pluripotent stem cells.
    Authors: Guang Et al.
    Cell Regen  2022;11:4
  7. Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis.
    Authors: Fernando Rodríguez Et al.
    Mol Neurobiol  2021;58:470-482
  8. α-Arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis.
    Authors: JoAnn Et al.
    J Cell Sci  2021;134
  9. A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression.
    Authors: Akoume Et al.
    Sci Rep  2019;9:10074
  10. Cortical contractility triggers a stochastic switch to fast amoeboid cell motility.
    Authors: Ruprecht Et al.
    J Clin Invest  2015;160:673


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