1-Oleoyl lysophosphatidic acid sodium salt

Catalog # Availability Size / Price Qty
3854/1
Lysophosphatidic Acid (LPA) Receptor Agonists Small Molecule
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Description: Endogenous agonist of LPA1 and LPA2

Chemical Name: 1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt

Product Details
Citations (1)
Supplemental Products
Reviews (3)

Biological Activity

Endogenous agonist of the lysophospholipid receptors LPA1 and LPA2. Inhibits differentiation of neural stem cells (NSCs) into neurons.

Technical Data

M.Wt:
458.5
Formula:
C21H40NaO7P
Solubility:
Soluble to 10 mM in phosphate buffered saline
Storage:
Store at -20°C
CAS No:
325465-93-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for 1-Oleoyl lysophosphatidic acid sodium salt

The citations listed below are publications that use Tocris products. Selected citations for 1-Oleoyl lysophosphatidic acid sodium salt include:

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LPA induces COX-2 expression in osteosacroma cells
By Anonymous on 12/13/2018
Species: Human

MG-63 cells were pre-incubated with indicated inhibitors for 30 min followed by treatment with 10 µM LPA for 3 h to follow COX-2 expression using Western blot. All inhibitors prevented COX-2 induction by LPA.


Works to deplete stem cell pool
By Anonymous on 11/18/2018
Species: Mouse

Primary mouse mammary glands were digested, incubated with LPA or control at 5uM and then analyzed using CD24/CD29 to identify effects on the stem cell pool. A 50% reduction in the stem cell pool (p4) was identified after LPA treatment.


LPA induces COX-2 expression in MG-63 cells
By Christopher Trummer on 10/23/2018
Species: Human

MG-63 cells were treated with 10 µM LPA (0-48 h) to follow COX-2 expression using Western blot. LPA induced COX-2 expression in a time-dependent manner in osteosarcoma cells.


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