10058-F4

Tocris Bioscience | Catalog # 4406

Inhibits c-Myc-Max dimerization
Tocris Bioscience

Key Product Details

Description

Inhibits c-Myc-Max dimerization
View all MYC Inhibitors »

Product Description

10058-F4 is a cell permeable c-Myc-Max dimerization inhibitor. Inhibits proliferation, induces apoptosis and arrests cells in G0/G1 in rat1a-c-Myc cells. Also reduces tumor growth in vivo. In lymphoma cells, 10058-F4 decreases glucose uptake and expression of glycolysis-associated genes and reduces cell viability.

Product Specifications for 10058-F4

Molecular Weight

249.35

Formula

C12H11NOS2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone

CAS Number

403811-55-2

PubChem ID

1271002

InChI Key

SVXDHPADAXBMFB-JXMROGBWSA-N

SMILES

O=C(NC(S2)=S)/C2=C\C1=CC=C(CC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.93 100
Ethanol 4.99 20

Preparing Stock Solutions for 10058-F4

The following data is based on the product molecular weight 249.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.01 mL 20.05 mL 40.10 mL
5 mM 0.80 mL 4.01 mL 8.02 mL
10 mM 0.40 mL 2.01 mL 4.01 mL
50 mM 0.08 mL 0.40 mL 0.80 mL

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Product Documents for 10058-F4

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 10058-F4

For research use only

Customer Reviews for 10058-F4 (1)

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  • works perfectly
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 07/28/2019
    Used the compound for studying the anti-cancer properties. The compound 10058-F4, strongly induced caspase‐3‐dependent apoptosis in pre‐B ALL cells.

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