15-deoxy-Δ-12,14-Prostaglandin J2

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15-deoxy-Δ-12,14-Prostaglandin J2 | CAS No. 87893-55-8 | PPAR gamma Receptor Agonists
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Description: Endogenous PPARγ agonist

Chemical Name: (5Z,12E,14E)-11-Oxo-prosta-5,9,12,14-tetraen-1-oic acid

Purity: ≥95%

Product Details
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Reviews (1)

Biological Activity

Selective PPARγ agonist that induces adipocyte differentiation in C3H10Y1/2 fibroblasts (EC50 = 7 μM).

Technical Data

M.Wt:
316.44
Formula:
C20H28O3
Solubility:
Soluble in Methyl acetate (supplied pre-dissolved - 1mg/ml)
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
87893-55-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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15d-PGJ2 promotes MAPK activation in cardiomyocytes
By Chintan Koyani on 10/13/2018
Species: Mouse

Treatment of HL-1 cells (15 min) with increasing 15d-PGJ2 concentrations induced phosphorylation of p38 and p42/44 MAPK (shown in Image). A As pronounced MAPK activation was observed at 15 μM 15d-PGJ2.

PMID: 24698234

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