15-deoxy-Δ-12,14-Prostaglandin J2

Tocris Bioscience | Catalog # 2306

Endogenous PPARγ agonist
Tocris Bioscience
Discontinued Product
2306 has been discontinued. View all PPAR gamma Receptor Agonists products.

Key Product Details

Description

Endogenous PPARγ agonist
View all PPAR gamma Receptor Agonists »

Product Description

15-deoxy-Δ-12,14-Prostaglandin J2 is a selective PPARγ agonist that induces adipocyte differentiation in C3H10Y1/2 fibroblasts (EC50 = 7 μM).

Product Specifications for 15-deoxy-Δ-12,14-Prostaglandin J2

Molecular Weight

316.44

Formula

C20H28O3

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(5Z,12E,14E)-11-Oxo-prosta-5,9,12,14-tetraen-1-oic acid

CAS Number

87893-55-8

PubChem ID

5311211

InChI Key

VHRUMKCAEVRUBK-GODQJPCRSA-N

SMILES

O=C/1C=C[C@@H](C1=C/C=C/CCCCC)C/C=C\CCCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in Methyl acetate (supplied pre-dissolved - 1mg/ml)

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Background References

References are publications that support the biological activity of the product.

Product Documents for 15-deoxy-Δ-12,14-Prostaglandin J2

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 15-deoxy-Δ-12,14-Prostaglandin J2

For research use only

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  • 15d-PGJ2 promotes MAPK activation in cardiomyocytes
    Name: Chintan Koyani
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Cardiomyocytes
    Verified Customer | Posted 10/13/2018
    Treatment of HL-1 cells (15 min) with increasing 15d-PGJ2 concentrations induced phosphorylation of p38 and p42/44 MAPK (shown in Image). A As pronounced MAPK activation was observed at 15 μM 15d-PGJ2.
    15-deoxy-Δ-12,14-Prostaglandin J2 2306

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