16673-34-0 NLRP3i

Catalog # Availability Size / Price Qty
6774/50
6774/10
Inflammasomes Inhibitors Small Molecule
1 Image
Description: NLRP3 inflammasome inhibitor

Chemical Name: N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

NLRP3 inflammasome inhibitor. Inhibits formation of NLRP3 inflammasome and IL-1β release in LPS and ATP-stimulated mouse macrophages and cardiomyocytes in vitro. Inhibits NLRP3 activation in mouse acute myocardial infarction and peritonitis models without affecting plasma glucose levels. Glyburide synthetic intermediate.

Technical Data

M.Wt:
368.84
Formula:
C16H17ClN2O4S
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
16673-34-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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