17-DMAG hydrochloride

Catalog # Availability Size / Price Qty
2610/1
Cat.No. 2610 - 17-DMAG hydrochloride | C32H48N4O8.HCl | CAS No. 467214-21-7
1 Image
Description: Water-soluble Hsp90 inhibitor
Alternative Names: NSC 707545

Chemical Name: 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin hydrochloride

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Water-soluble analog of 17-AAG (Cat. No. 1515) and geldanamycin (Cat. No. 1368). Binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively).

Technical Data

M.Wt:
653.21
Formula:
C32H48N4O8.HCl
Solubility:
Soluble to 30 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Desiccate at -20°C
CAS No:
467214-21-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold with the permission of the NIH, US Patent 6,890,917

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for 17-DMAG hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for 17-DMAG hydrochloride include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for 17-DMAG hydrochloride

There are currently no reviews for this product. Be the first to review 17-DMAG hydrochloride and earn rewards!

Have you used 17-DMAG hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.