High affinity and extremely selective A3
adenosine receptor agonist (Ki
= 0.33 nM). Displays 2500- and 1400-fold selectivity over A1
receptors respectively. Exhibits high selectivity over the Na+
-independent adenosine transporter.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold with the permission of the NIH, US Patent 08/091,109
Adenosine A3 receptors: novel ligands and paradoxical effects.
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
Kim et al.
Hemodynamic effects of histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats.
Schaick et al.
The citations listed below are publications that use Tocris products. Selected citations for 2-Cl-IB-MECA include:
Showing Results 1 - 10 of 12