2-Iodomelatonin

  ( 3 citations )    
Product Datasheet
Catalog Number:0737
Chemical Name:N-[2-(2-Iodo-5-methoxyindol-3-yl)ethyl]acetamide
Product Details
Citations (3)
Reviews
Biological Activity
Potent melatonin agonist (pKi values are 10.55 and 9.87 at human recombinant MT1 and MT2 receptors respectively). 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
Technical Data
  • M.Wt:
    358.18
  • Formula:
    C13H15IN2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    93515-00-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for 2-Iodomelatonin include:

3 Citations: Showing 1 - 3
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  1. Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats.
    Authors: Hou Et al.
    Front Cell Neurosci  2017;11:98
  2. Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
    Authors: Calamini Et al.
    Biochem J  2008;413:81
  3. Identification of the melatonin-binding site MT3 as the quinone reductase 2.
    Authors: Nosjean Et al.
    J Biol Chem  2000;275:31311

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