A very potent and selective ligand for the D2
= 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D2
and a 12-fold lower affinity at 5-HT2
Soluble to 25 mM in DMSO
Store at RT
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All Tocris products are intended for laboratory research use only.
Effect of N-alkylation on the affinities of analogues of spiperone for dopamine D2 and serotonin 5-HT2 receptors.
Mach et al.