4-Chlorophenylguanidine hydrochloride

Key Product Details

Product Description

4-Chlorophenylguanidine hydrochloride is a potent inhibitor of urokinase. Also a positive allosteric modulator at acid sensing ion channel 3 (ASIC3), which increases its pH sensitivity.

Product Specifications for 4-Chlorophenylguanidine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 4-Chlorophenylguanidine hydrochloride

The following data is based on the product molecular weight 206.07.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.85 mL	24.26 mL	48.53 mL
5 mM	0.97 mL	4.85 mL	9.71 mL
10 mM	0.49 mL	2.43 mL	4.85 mL
50 mM	0.10 mL	0.49 mL	0.97 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Agharkar & Gonzales 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J.Pharmacol.Sci. 2017 PMID: 28259560
• Yang Selective inhibition of urok. by substituted phenylguanidines: quantitative structure-activity relationship analyses. J.Med.Chem. 1990 PMID: 2231595

Product Documents for 4-Chlorophenylguanidine hydrochloride