4-CMTB

Catalog # Availability Size / Price Qty
4642/10
4642/50
Cat.No. 4642 - 4-CMTB | C14H15ClN2OS | CAS No. 300851-67-6
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Description: FFA2 agonist; also exhibits positive allosteric modulatory activity

Chemical Name: 4-chloro-α-(1-methylethyl)-N-2-thiazolylbenzeneacetamide

Purity: ≥98%

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Biological Activity

Free fatty acid receptor FFA2 agonist (pEC50 = 6.38) and positive allosteric modulator. Binds at a site distinct from the orthosteric site; modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2).

Technical Data

M.Wt:
294.8
Formula:
C14H15ClN2OS
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
300851-67-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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