4-Octyl itaconate

Tocris Bioscience | Catalog # 6662

Nrf2 activator; cell permeable
Tocris Bioscience

Key Product Details

Description

Nrf2 activator; cell permeable
View all Nrf2 Activators »

Product Description

4-Octyl itaconate activates Nrf2. Inhibits LPS-induced increases in IL-1β mRNA, HIF-1α and IL-10 in macrophages. Decreases cytokine production in response to LPS in mice and prolongs survival. Cell permeable.

Product Specifications for 4-Octyl itaconate

Molecular Weight

242.31

Formula

C13H22O4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-Methylenebutanedioic acid 4-octyl ester

CAS Number

3133-16-2

PubChem ID

14239884

InChI Key

KBASUIDPDITQHT-UHFFFAOYSA-N

SMILES

CCCCCCCCOC(CC(C(O)=O)=C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.23 100

Preparing Stock Solutions for 4-Octyl itaconate

The following data is based on the product molecular weight 242.31.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.13 mL 20.63 mL 41.27 mL
5 mM 0.83 mL 4.13 mL 8.25 mL
10 mM 0.41 mL 2.06 mL 4.13 mL
50 mM 0.08 mL 0.41 mL 0.83 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for 4-Octyl itaconate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 4-Octyl itaconate

For research use only

Citations for 4-Octyl itaconate

Customer Reviews for 4-Octyl itaconate (1)

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  • Good product
    Name: Rabina Mainali
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: C2C12
    Verified Customer | Posted 09/22/2022
    In vitro treatment of C2C12 cells. The image shows the effects of dimethyl itaconate (DMI) and 4-Octyl itaconate (4-OI) on myogenesis
    4-Octyl itaconate 6662

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