4,4-Pentamethylenepiperidine hydrochloride

Key Product Details

Product Description

M2 proton channel blocker (IC₅₀ = 0.92 μM). Inhibits influenza virus M2 protein (AM2).

Product Specifications for 4,4-Pentamethylenepiperidine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 4,4-Pentamethylenepiperidine hydrochloride

The following data is based on the product molecular weight 189.73.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.27 mL	26.35 mL	52.71 mL
5 mM	1.05 mL	5.27 mL	10.54 mL
10 mM	0.53 mL	2.64 mL	5.27 mL
50 mM	0.11 mL	0.53 mL	1.05 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Wang Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from Influenza A Virus. J.Am.Chem.Soc. 2009 PMID: 19469531

Product Documents for 4,4-Pentamethylenepiperidine hydrochloride