Allosteric agonist at α
7 nAChR. Binds at a separate site and exhibits more efficacious receptor agonism compared to acetylcholine
(Cat. No. 2809), displays 8-fold lower EC50
value and 45-fold larger maximal response.
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All Tocris products are intended for laboratory research use only.
Agonist activation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site.
Gill et al.
The citations listed below are publications that use Tocris products. Selected citations for 4BP-TQS include:
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