5-Azacytidine

Catalog # Availability Size / Price Qty
3842/50
Cat.No. 3842 - 5-Azacytidine | C8H12N4O5 | CAS No. 320-67-2
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Description: DNA methyltransferase inhibitor

Chemical Name: 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Purity: ≥98%

Product Details
Citations (4)
Reviews

Biological Activity

DNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells; induces differentiation of mesenchymal stem cells into cardiomyocytes.

Technical Data

M.Wt:
244.2
Formula:
C8H12N4O5
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
320-67-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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⚠ WARNING: This product can expose you to chemicals including Azacitidine, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

Citations for 5-Azacytidine

The citations listed below are publications that use Tocris products. Selected citations for 5-Azacytidine include:

4 Citations: Showing 1 - 4

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