5-Carboxamidotryptamine maleate

Catalog # Availability Size / Price Qty
0458/10
0458/50
Cat.No. 0458 - 5-Carboxamidotryptamine maleate | C11H13N3O.C4H4O4 | CAS No. 74885-72-6
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Description: 5-HT1 agonist. Also has high affinity for 5-ht5a and 5-HT7
Alternative Names: AH-21467, 5-CT

Purity: ≥99%

Product Details
Citations (14)
Supplemental Products
Reviews

Biological Activity

5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B, 5-HT1D, 5-ht5 and 5-HT7 receptors.

Technical Data

M.Wt:
319.32
Formula:
C11H13N3O.C4H4O4
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
74885-72-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

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Citations for 5-Carboxamidotryptamine maleate

The citations listed below are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:

14 Citations: Showing 1 - 10

  1. Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix
    Authors: Bijata Et al.
    Cell Rep  2017;19:1767
  2. Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
    Authors: Sargin Et al.
    Elife  2016;5:e21416
  3. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
    Authors: Chan Et al.
    PLoS Pathog  2016;12:e1005651
  4. 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts.
    Authors: Chien and Su
    PLoS One  2015;22:42
  5. Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
    Authors: Montalbano Et al.
    Br J Pharmacol  2015;10:e0140369
  6. Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor.
    Authors: Gantz Et al.
    Am J Physiol Renal Physiol  2013;78:807
  7. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim Et al.
    Neuron  2013;190:4795
  8. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  9. 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo.
    Authors: Müller Et al.
    PLoS One  2009;4:e6453
  10. Serotonin targets inhibitory synapses to induce modulation of network functions.
    Authors: Manzke Et al.
    Philos Trans R Soc Lond B Biol Sci  2009;364:2589

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