5-Carboxamidotryptamine maleate

  ( 14 citations )    
Product Datasheet
Catalog Number:0458
Alternate Names:AH-21467, 5-CT
Chemical Name:
Product Details
Citations (14)
Supplemental Products
Reviews
Biological Activity
5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B, 5-HT1D, 5-ht5 and 5-HT7 receptors.
Technical Data
  • M.Wt:
    319.32
  • Formula:
    C11H13N3O.C4H4O4
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    74885-72-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:

14 Citations: Showing 1 - 10
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  1. Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix
    Authors: Bijata Et al.
    Cell Rep  2017;19:1767
  2. Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
    Authors: Sargin Et al.
    Elife  2016;5:e21416
  3. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
    Authors: Chan Et al.
    PLoS Pathog  2016;12:e1005651
  4. 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts.
    Authors: Chien and Su
    PLoS One  2015;22:42
  5. Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
    Authors: Montalbano Et al.
    Br J Pharmacol  2015;10:e0140369
  6. Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor.
    Authors: Gantz Et al.
    Am J Physiol Renal Physiol  2013;78:807
  7. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim Et al.
    Neuron  2013;190:4795
  8. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  9. 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo.
    Authors: Müller Et al.
    PLoS One  2009;4:e6453
  10. Serotonin targets inhibitory synapses to induce modulation of network functions.
    Authors: Manzke Et al.
    Philos Trans R Soc Lond B Biol Sci  2009;364:2589
  11. Frequency-dependent modulation of retinogeniculate transmission by serotonin.
    Authors: Seeburg Et al.
    J Neurosci  2004;24:10950
  12. Increased contractile response to 5-hydroxytryptamine1-receptor stimulation in pulmonary arteries from chronic hypoxic rats: role of pharmacological synergy.
    Authors: Maclean and Morecroft
    Br J Pharmacol  2001;134:614
  13. 5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor.
    Authors: Morecroft Et al.
    J Immunol  1999;128:730
  14. Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
    Authors: Geerts Et al.
    Br J Pharmacol  1999;127:1327
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