Biological Activity5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B, 5-HT1D, 5-ht5 and 5-HT7 receptors.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
An investigation of the 5-HT1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxyamidotryptamine and sumatriptan in the central nervous system of seven species.
Beer et al.
[3H]-5-carboxamidotryptamine labels 5HT1D binding sites in bovine substantia nigra.
Nowak et al.
Zifa and Fillion
Antagonist activity of meta-chlorophenylpiperazine and partial agonist activity of 8-OH-DPAT at the 5-HT7 receptor.
Wood et al.
Citations for 5-Carboxamidotryptamine maleate
The citations listed below are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:
14 Citations: Showing 1 - 10
Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix
Authors: Bijata Et al.
Cell Rep 2017;19:1767
Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
Authors: Sargin Et al.
A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
Authors: Chan Et al.
PLoS Pathog 2016;12:e1005651
5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts.
Authors: Chien and Su
PLoS One 2015;22:42
Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
Authors: Montalbano Et al.
Br J Pharmacol 2015;10:e0140369
Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor.
Authors: Gantz Et al.
Am J Physiol Renal Physiol 2013;78:807
Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
Authors: Kim Et al.
Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
Authors: Murray Et al.
J Neurophysiol 2011;106:925
5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo.
Authors: Müller Et al.
PLoS One 2009;4:e6453
Serotonin targets inhibitory synapses to induce modulation of network functions.
Authors: Manzke Et al.
Philos Trans R Soc Lond B Biol Sci 2009;364:2589
Frequency-dependent modulation of retinogeniculate transmission by serotonin.
Authors: Seeburg Et al.
J Neurosci 2004;24:10950
Increased contractile response to 5-hydroxytryptamine1-receptor stimulation in pulmonary arteries from chronic hypoxic rats: role of pharmacological synergy.
Authors: Maclean and Morecroft
Br J Pharmacol 2001;134:614
5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor.
Authors: Morecroft Et al.
J Immunol 1999;128:730
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Authors: Geerts Et al.
Br J Pharmacol 1999;127:1327
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for 5-Carboxamidotryptamine maleate
There are currently no reviews for this product. Be the first to review 5-Carboxamidotryptamine maleate and earn rewards!
Have you used 5-Carboxamidotryptamine maleate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image