Biological Activity5-Carboxamidotryptamine maleate is a 5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B, 5-HT1D, 5-ht5 and 5-HT7 receptors.
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[3H]-5-carboxamidotryptamine labels 5HT1D binding sites in bovine substantia nigra.
Nowak et al.
Antagonist activity of meta-chlorophenylpiperazine and partial agonist activity of 8-OH-DPAT at the 5-HT7 receptor.
Wood et al.
Zifa and Fillion
An investigation of the 5-HT1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxyamidotryptamine and sumatr. in the central nervous system of seven species.
Beer et al.
Citations for 5-Carboxamidotryptamine maleate
The citations listed below are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:
14 Citations: Showing 1 - 10
Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix
Authors: Bijata Et al.
Cell Rep 2017;19:1767
Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
Authors: Sargin Et al.
A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
Authors: Chan Et al.
PLoS Pathog 2016;12:e1005651
5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts.
Authors: Chien and Su
PLoS One 2015;22:42
Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
Authors: Montalbano Et al.
Br J Pharmacol 2015;10:e0140369
Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor.
Authors: Gantz Et al.
Am J Physiol Renal Physiol 2013;78:807
Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
Authors: Kim Et al.
Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
Authors: Murray Et al.
J Neurophysiol 2011;106:925
5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo.
Authors: Müller Et al.
PLoS One 2009;4:e6453
Serotonin targets inhibitory synapses to induce modulation of network functions.
Authors: Manzke Et al.
Philos Trans R Soc Lond B Biol Sci 2009;364:2589
Frequency-dependent modulation of retinogeniculate transmission by serotonin.
Authors: Seeburg Et al.
J Neurosci 2004;24:10950
Increased contractile response to 5-hydroxytryptamine1-receptor stimulation in pulmonary arteries from chronic hypoxic rats: role of pharmacological synergy.
Authors: Maclean and Morecroft
Br J Pharmacol 2001;134:614
5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor.
Authors: Morecroft Et al.
J Immunol 1999;128:730
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Authors: Geerts Et al.
Br J Pharmacol 1999;127:1327
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