5-HT4 Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-78403PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
View all 5-HT4 Proteins and Enzymes »

Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NBP1-78403. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NBP1-78403 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-78403PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: 5-HT4

The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358). A ninth isoform (5-HT4H) results in the insertion of 14 amino acids into the second intracellular loop. 5-HT4 receptor expression has been documented primarily in the brain, and in colon, heart, and vessel. An EST has been isolated from a human cancerous nerve library.

Long Name

5-Hydroxytryptamine Receptor 4

Alternate Names

5HT4, HTR4

Gene Symbol

HTR4

Additional 5-HT4 Products

Product Documents for 5-HT4 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for 5-HT4 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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