6-Hydroxy-DL-DOPA

Catalog # Availability Size / Price Qty
5740/10
5740/50
Cat.No. 5740 - 6-Hydroxy-DL-DOPA | C9H11NO5 | CAS No. 21373-30-8
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Description: Allosteric inhibitor of RAD52; also APE1 inhibitor

Chemical Name: 2,5-Dihydroxy-DL-tyrosine

Product Details
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Biological Activity

Allosteric inhibitor of RAD52; inhibits RAD52 binding to single strand DNA binding domains (IC50 = 1.1 μM). Selectively inhibits proliferation of BRCA-deficient cancer cells in vitro. Also inhibits APE1.

Technical Data

M.Wt:
213.19
Formula:
C9H11NO5
Solubility:
Soluble to 100 mM in 1M HCl
Storage:
Store at -20°C
CAS No:
21373-30-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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