Potent and selective CREB inhibitor (IC50
= 81 nM). Inhibits cancer cell growth, without harming normal cells (up to 1 μ
M). Completely suppresses tumor growth in a breast cancer xenograft model.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
Identification of a potent inhibitor of CREB-mediated gene transcription with efficacious in vivo anticancer activity
Xie et al.