666-15

Catalog # Availability Size / Price Qty
5661/10
5661/50
Cat.No. 5661 - 666-15 | C33H30ClN3O5.HCl | CAS No. 1433286-70-4
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Description: Potent and selective CREB inhibitor

Chemical Name: 3-(3-Aminopropoxy)-N-[2-[[3-[[(4-chloro-2-hydroxyphenyl)amino]carbonyl]-2-naphthalenyl]oxy]ethyl]-2-naphthalenecarboxamide hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews (1)

Biological Activity

Potent and selective CREB inhibitor (IC50 = 81 nM). Inhibits cancer cell growth, without harming normal cells (up to 1 μM). Completely suppresses tumor growth in a breast cancer xenograft model.

Technical Data

M.Wt:
620.52
Formula:
C33H30ClN3O5.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1433286-70-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for 666-15

The citations listed below are publications that use Tocris products. Selected citations for 666-15 include:

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creb inhibitor
By Anonymous on 05/02/2018
Species: Mouse

drug treatment with different conc from 1nm-5um


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