Catalog Number: 0706
Chemical Name: (±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide
Biological Activity
D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively). (R)-(+)-8-Hydroxy-DPAT hydrobromide (Cat. No. 1080) and 8-Hydroxy-DPAT hydrobromide (Cat. No 0529) also available.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Behavioural effects of the D3 dopamine receptor agonist 7-OH-DPAT in relation to other D2-like agonists.
    Daly and Waddington
    Neuropharmacology, 1993;32:509
  2. Aminotetralin drugs and D3 receptor fuctions.
    Biochem.Pharmacol., 1996;52:511
  3. Identification, characterization, and localization of the dopamine D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin.
    Levesque et al.
    Proc.Natl.Acad.Sci.U.S.A., 1992;89:8155
  4. Dopamine receptor pharmacology.
    Seeman and Van Tol
    Trends Pharmacol.Sci., 1994;15:264
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