Chemical Name: (±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide
Biological Activity7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively).
8-Hydroxy Isomer also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Behavioural effects of the D3 DA receptor agonist 7-OH-DPAT in relation to other D2-like agonists.
Daly and Waddington
Aminotetralin drugs and D3 receptor fuctions.
Identification, characterization, and localization of the DA D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin.
Levesque et al.
DA receptor pharmacology.
Seeman and Van Tol
Trends Pharmacol.Sci., 1994;15:264
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