Cell-permeable phosphopeptide activator of PI 3-kinase. Binds with high affinity to p85 subunit of the enzyme. Displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro
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Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway.
Williams and Doherty
Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide.
Derossi et al.
The citations listed below are publications that use Tocris products. Selected citations for 740 Y-P include:
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