740 Y-P

  ( 8 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:1983
Alternate Names:PDGFR740Y-P
Chemical Name:
Product Details
Citations (8)
Biological Activity
Cell-permeable phosphopeptide activator of PI 3-kinase. Binds with high affinity to p85 subunit of the enzyme. Displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Tyr-21 = pTyr)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
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The citations listed below are publications that use Tocris products. Selected citations for 740 Y-P include:

8 Citations: Showing 1 - 8
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  1. Thyroid hormone inhibits the proliferation of piglet Sertoli cell via PI3K signaling pathway.
    Authors: Sun Et al.
    J Assist Reprod Genet  2015;83:86
  2. Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.
    Authors: Lomakin Et al.
    Nat Cell Biol  2015;17:1435
  3. New strategy for in vitro activation of primordial follicles with mTOR and PI3K stimulators.
    Authors: Sun Et al.
    Cell Cycle  2015;14:721
  4. Attempted application of bioengineered/biosynthetic supporting matrices with phosphatidylinositol-trisphosphate-enhancing substances to organ culture of human primordial follicles.
    Authors: Lerer-Serfaty Et al.
    Proc Natl Acad Sci U S A  2013;30:1279
  5. Age-dependent regulation of synaptic connections by dopamine D2 receptors.
    Authors: Jia Et al.
    Nat Neurosci  2013;16:1627
  6. The expression and relaxant effect of bitter taste receptors in human bronchi.
    Authors: Grassin-Delyle Et al.
    Respir Res  2013;14:134
  7. Apoptosis resistance and PKC signaling: distinguishing features of high and low metastatic cells.
    Authors: Hong Et al.
    Neoplasia  2012;14:249
  8. Activation of dormant ovarian follicles to generate mature eggs.
    Authors: Li Et al.
    Nat Commun  2010;107:10280


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Average Rating: 3 (Based on 1 review)

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  Human Anonymous 07/12/2018


Species Human

Other Experimental Details

Other Experimental Details Not sure if it is working or notWish larger amounts with discount were available

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