8-Bromo-cGMP, sodium salt
Chemical Name: 8-Bromoguanosine cyclic 3',5'-monophosphate sodium salt
Biological Activity8-Bromo-cGMP, sodium salt is a membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP.
Buchan et al.
Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3',5'-guanosine monophosphate.
Ignarro et al.
Relaxation of pig coronary arteries by new and potent cGMP analogs that selectively activate type 1α, compared with type 1β, cGMP-dependent protein kinase.
Sekhar et al.
Citations for 8-Bromo-cGMP, sodium salt
The citations listed below are publications that use Tocris products. Selected citations for 8-Bromo-cGMP, sodium salt include:
3 Citations: Showing 1 - 3
Nitric oxide-mediated modulation of the murine locomotor network.
Authors: Foster Et al.
J Neurophysiol 2014;111:659
Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex.
Authors: Huang and Hsu
Cereb Cortex 2010;20:982
Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology.
Authors: Capuano Et al.
Mol Pain 2009;5:43
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