Home / Integrin Receptor Inhibitors / A 286982

A 286982

Catalog #: 4228 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4228/10
4228/50
A 286982 | CAS No. 280749-17-9 | Integrin Receptor Inhibitors
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Description: Potent inhibitor of the LFA-1/ICAM-1 interaction

Chemical Name: (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one

Purity: ≥99%

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Biological Activity

A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays respectively).

Technical Data

M.Wt:
453.55
Formula:
C24H27N3O4S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
280749-17-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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FAQs

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VersaClone cDNA Plasmids

Human ICAM-1/CD54 (NP_000192) VersaClone cDNA

RDC1030
2 Citations

Human Integrin beta 2/CD18 (NP_000202) VersaClone cDNA

RDC0398

Mouse ICAM-1/CD54 (NP_034623) VersaClone cDNA

RDC1449

Mouse Integrin beta 2/CD18 (NP_032430) VersaClone cDNA

RDC1476

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