A 779

Catalog # Availability Size / Price Qty
5937/5
Cat.No. 5937 - A 779 | Asp-Arg-Val-Tyr-Ile-His-D-Ala | CAS No. 159432-28-7
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Description: Selective Mas receptor (Ang-(1-7) receptor) antagonist
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Biological Activity

Selective Mas receptor (Ang-(1-7) receptor) antagonist. Exhibits no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Inhibits antidiuretic effect of Ang-(1-7) in water-loaded rats. Also attenuates Monocrotaline-induced pulmonary fibrosis in rats.

Technical Data

M.Wt:
872.98
Formula:
C39H60N12O11
Sequence:
DRVYIHA

(Modifications: Ala-7 = D-Ala)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
159432-28-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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