Catalog Number: 5937
Biological Activity
Selective Mas receptor (Ang-(1-7) receptor) antagonist. Exhibits no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Inhibits antidiuretic effect of Ang-(1-7) in water-loaded rats. Also attenuates Monocrotaline-induced pulmonary fibrosis in rats.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Ala-7 = D-Ala)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
    Bruce et al.
    Br.J.Pharmacol., 2015;172:2219
  2. Cardiovascular effects of angiotensin II and angiotensin-(1-7) at the RVLM of trained normotensive rats.
    Becker et al.
    Brain Res., 2005;1040:121
  3. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors.
    Santos et al.
    Brain Res.Bull., 1994;35:293
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information