A 844606

   
Product Datasheet
Catalog Number:4477
Chemical Name:2-(Hexahydro-5-methylpyrrolo[3,4-c]pyrrol-2(1H)-yl)-9H-xanthen-9-one
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Biological Activity
Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist (EC50 values are 1.4 and 2.2 μM at human and rat receptors respectively). Displays no measurable effect on α4β2 nAChRs. Stimulates α7 nAChR-induced ERK1/2 phosphorylation in PC12 cells.
Technical Data
  • M.Wt:
    320.38
  • Formula:
    C20H20N2O2
  • Solubility:
    Soluble to 5 mM in ethanol with gentle warming
  • Purity:
    >99
  • Storage:
    Store at -20°C
  • CAS No:
    861119-08-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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