Chemical Name: N-(2-Hydroxy-5-methylphenyl)benzenepropanamide
Biological ActivityAA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.
Plate et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for AA 147
There are currently no reviews for this product. Be the first to review AA 147 and earn rewards!
Have you used AA 147?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image