Chemical Name: N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
Biological ActivityUnnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUA pairs.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid.
Ai et al.
Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells.
Chatterjee et al.
Visualizing protein partnerships in living cells and organisms.
Lowder et al.
Curr.Opin.Cell Biol., 2011;15:781
A chemical proteomics approach to reveal direct protein-protein interactions in living cells.
Kleiner et al.
Cell Chem.Biol., 2018;25:110
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