Catalog Number: 5113
Chemical Name: N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
Biological Activity
Unnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUA pairs.
Technical Data
  • M.Wt:
    272.3
  • Formula:
    C11H20N4O4.CF3CO2H
  • Solubility:
    Soluble to 10 mM in water with gentle warming and to 100 mM in 1eq. HCl
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1253643-88-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Visualizing protein partnerships in living cells and organisms.
    Lowder et al.
    Curr.Opin.Cell Biol., 2011;15:781
  2. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells.
    Chatterjee et al.
    Proc.Natl.Acad.Sci.U.S.A., 2013;110:11803
  3. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid.
    Ai et al.
    Chembiochem, 2011;12:1854

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