Biological Activity Antimitotic agent, inhibits microtubule polymerization. Binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis. Exhibits antitumor activity. Also displays activity in cell lines resistant to vincristine, doxorubicin and cisplatin. Orally bioavailable.
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Store at +4°C
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For batch specific data refer to the Certificate of Analysis.
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