Catalog Number: 1387
Biological Activity
Potent, selective partial agonist peptide for the NOP receptor (Ki = 0.71 nM). Selective over μ, δ and κ opioid receptors (IC50 > 4000 nM). Increases food intake in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Arg-1 = C-terminal Ac, Lys-6 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1.
    Dooley et al.
    J.Pharmacol.Exp.Ther., 1997;283:735
  2. Characterization of the ORL1 receptor on adrenergic nerve in the rat anococcygeus.
    Ho et al.
    Br.J.Pharmacol., 2000;131:349
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