Ac-Trp-Leu-Ala-AMC (Ac-WLA-AMC)

Discontinued Product

S-330 has been discontinued.
View all Proteasome Substrates products.
Product Details
Citations (2)
FAQs
Reviews (1)

Ac-Trp-Leu-Ala-AMC (Ac-WLA-AMC) Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-Species

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Citations for Ac-Trp-Leu-Ala-AMC (Ac-WLA-AMC)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth
    Authors: MJ Lee, Z Miller, JE Park, D Bhattarai, W Lee, KB Kim
    Sci Rep, 2019-03-11;9(1):4089.  2019-03-11
  2. Immunoproteasome functions explained by divergence in cleavage specificity and regulation
    Authors: MB Winter, F La Greca, S Arastu-Kap, F Caiazza, P Cimermanci, TJ Buchholz, JL Anderl, M Ravalin, MF Bohn, A Sali, AJ O'Donoghue, CS Craik
    Elife, 2017-11-28;6(0):.  2017-11-28

FAQs

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Reviews for Ac-Trp-Leu-Ala-AMC (Ac-WLA-AMC)

Average Rating: 3 (Based on 1 Review)

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Ac-Trp-Leu-Ala-AMC (Ac-WLA-AMC)
By TAKASHI SHIMADA on 05/02/2020

S-330 hydrolysis confirmation by LCMS-SRM
S-330: 1 uM
i20S: 15 nM
PA28a: 150 nM
Reaction: 37 °C for 5 h
1:S-330 Ac-WLA-AMC (588.20>342.15)
2:Free AMC (176.25>120.00)
3:S-330 Ac-WLA-COOH (431.25>342.15)