Chemical Name: 3-(Acetylamino)-1-propanesulfonic acid hemicalcium salt
Biological ActivityGABA receptor agonist and modulator of glutamatergic systems. Reduces alcohol consumption in animal models of alcohol addiction.
Deuterated analog also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat.
Spanagel et al.
Acamprosate enhances N-MthD.-aspartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons.
Berton et al.
Alcohol Clin.Exp.Res., 1998;22:183
Interaction of acampr. with ethanol and spermine on NMDA receptors in primary cultured neurons.
Popp and Lovinger
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