Catalog Number: 2673
Alternate Names: Bay-g 5421
Chemical Name: O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose
Biological Activity
Inhibitor of intestinal α-glucosidase (IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.
Technical Data
  • M.Wt:
    645.25
  • Formula:
    C25H43NO18
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Storage:
    Desiccate at RT
  • CAS No:
    56180-94-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase inhibitor acarbose (BAY g 5421).
    Krause et al.
    Digestion, 1982;23:232
  2. Acarbose: an update of its pharmacology and therapeutic use in diabetes mellitus.
    Balfour and McTavish
    Drugs, 1993;46:1025
  3. Evaluation of alpha-glucosidase inhibition by using an immobilized assay system.
    Oki et al.
    Biol.Pharm.Bull., 2000;23:1084

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