Acein

Name: Acein
Brand: Tocris Bioscience
SKU: 6006

Tocris Bioscience | Catalog # 6006

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Product Documents

High affinity angiotensin-converting enzyme (ACE) ligand

Discontinued Product

6006 has been discontinued. View all ACE Ligands products.

Technical Data
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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

High affinity angiotensin-converting enzyme (ACE) ligand

View all ACE Ligands »

Product Description

Acein is a high affinity angiotensin-converting enzyme (ACE) ligand (K_d = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Potentiates NMDA + D-serine-induced dopamine release from striatal slices in vitro and the striatum in vivo.

Product Specifications for Acein

Molecular Weight

932.50

Formula

C₄₃H₆₈N₁₀O₁₃

Storage

Store at -20°C

PubChem ID

122177132

InChI Key

VFPBWEDFCUSZRJ-BRCVGTSGSA-N

SMILES

[H]N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Neasta The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces DA release. Br.J.Pharmacol. 2016 PMID: 27027724

Product Documents for Acein

Certificate of Analysis

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Download SDS

Product Specific Notices for Acein

For research use only

Related Research Areas

Metalloproteases and Regulators

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