Catalog Number: 6006
Biological Activity
High affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Potentiates NMDA + D-serine-induced dopamine release from striatal slices in vitro and the striatum in vivo.
Technical Data
  • M.Wt:
    932.5
  • Formula:
    C43H68N10O13
  • Sequence:
    PPTTTKFAA
  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release.
    Neasta et al.
    Br.J.Pharmacol., 2016;173:1314

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