Agonist for group III mGlu receptors (EC50
values are 7.2 and 8.2 μ
M for mGlu4a
respectively). Anticonvulsant in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes.
Acher et al.
Pharmacological characterization of the rat metabotropic glutamate receptor 8a revealed strong similarities and slight differences with the type 4a receptor.
De Colle et al.
Anticonvulsant activity of a mGlu4α receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid.
Chapman et al.
The citations listed below are publications that use Tocris products. Selected citations for ACPT-I include:
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