ACPT-I

Key Product Details

Product Description

ACPT-I is a agonist for group III mGlu receptors (EC₅₀ values are 7.2 and 8.2 μM for mGlu_4a and mGlu₈ respectively). Anticonvulsant in mice.

Licensing Information

Sold with the permission of the CNRS

Product Specifications for ACPT-I

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ACPT-I

The following data is based on the product molecular weight 217.18.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	9.21 mL	46.04 mL	92.09 mL
2.5 mM	1.84 mL	9.21 mL	18.42 mL
5 mM	0.92 mL	4.60 mL	9.21 mL
25 mM	0.18 mL	0.92 mL	1.84 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

• Chapman Anticonvulsant activity of a mGlu_4α receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid. Eur.J.Pharmacol. 2001 PMID: 11476756
• De Colle Pharmacological characterization of the rat metabotropic glutamate receptor 8a revealed strong similarities and slight differences with the type 4a receptor. Eur.J.Pharmacol. 2000 PMID: 10771029
• Acher Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes. J.Med.Chem. 1997 PMID: 9301676

Product Documents for ACPT-I