Acridine Orange hydrochloride
Chemical Name: N,N,N',N'-Tetramethyl-3,6-acridinediamine hydrochloride
Biological ActivityCell and organelle membrane permeable nucleic acid binding dye. Emits green fluorescence when bound to double stranded DNA and red fluorescence when bound to RNA or single stranded DNA. Used in cell cycle and apoptosis studies and as a lysosomal dye.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression.
Kiyoshima et al.
PLoS ONE, 2013;8:80998
Analysis of single and double stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.
McMaster et al.
Rapid communication: oxidative stress induces apoptosis in embryonic cortical neurons.
Ratan et al.
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