Catalog Number: 5092
Chemical Name: N,N,N',N'-Tetramethyl-3,6-acridinediamine hydrochloride
Biological Activity
Cell and organelle membrane permeable nucleic acid binding dye. Emits green fluorescence when bound to double stranded DNA and red fluorescence when bound to RNA or single stranded DNA. Used in cell cycle and apoptosis studies and as a lysosomal dye.
Technical Data
  • M.Wt:
    301.81
  • Formula:
    C17H19N3.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    65-61-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression.
    Kiyoshima et al.
    PLoS ONE, 2013;8:80998
  2. Analysis of single and double stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.
    McMaster et al.
    Proc.Natl.Acad.Sci.USA, 1977;74:4835
  3. Rapid communication: oxidative stress induces apoptosis in embryonic cortical neurons.
    Ratan et al.
    J.Neurobiol., 2008;62:376

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