Activin RIA/ALK-2/Activin Receptor Type 1 Antibody Blocking Peptide

Novus Biologicals | Catalog # NB100-56432PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
View all Activin RIA/ALK-2 Proteins and Enzymes »

Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NB100-56432. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB100-56432 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB100-56432PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: Activin RIA/ALK-2

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Long Name

Activin Receptor IA

Alternate Names

ActivinRIA, ACVR1, ALK-2, ALK2

Gene Symbol

ACVR1

Additional Activin RIA/ALK-2 Products

Product Documents for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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