Adenine

Key Product Details

Product Description

Adenine is a high affinity adenine receptor agonist (K_i = 18 nM at rat adenine receptor). Inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor; also stimulates GTPγS binding (pEC₅₀ values are 8.54 and 7.21 respectively).

Product Specifications for Adenine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Adenine

The following data is based on the product molecular weight 171.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.83 mL	29.14 mL	58.28 mL
5 mM	1.17 mL	5.83 mL	11.66 mL
10 mM	0.58 mL	2.91 mL	5.83 mL
50 mM	0.12 mL	0.58 mL	1.17 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 52 publications citing the usage of this product.

• Bender Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc.Natl.Acad.Sci.
• Gorzalka Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol.Pharmacol. 2005 PMID: 15604413

Product Documents for Adenine