Chemical Name: 2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride
Biological ActivityAdipoRon hydrochloride is an agonist of adiponectin receptors AdipoR1 and AdipoR2 (Kd values are 1.8 and 3.1 μM respectively). Activates AMPK and PPARα signaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance in db/db mice. Orally active antidiabetic agent.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
Okada-Iwabu et al.
Citation for AdipoRon hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for AdipoRon hydrochloride include:
1 Citation: Showing 1 - 1
Iron induces ins. resistance in cardiomyocytes via regulation of oxidative stress.
Authors: Sung Et al.
Sci Rep 2019;9:4668
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