AdipoRon hydrochloride

Tocris Bioscience | Catalog # 5096

Orally active AdipoR1 and AdipoR2 agonist; antidiabetic
Tocris Bioscience

Key Product Details

Description

Orally active AdipoR1 and AdipoR2 agonist; antidiabetic
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Product Description

AdipoRon hydrochloride is an agonist of adiponectin receptors AdipoR1 and AdipoR2 (Kd values are 1.8 and 3.1 μM respectively). Activates AMPK and PPARα signaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance in db/db mice. Orally active antidiabetic agent.

Product Specifications for AdipoRon hydrochloride

Molecular Weight

464.98

Formula

C27H28N2O3.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride

CAS Number

1781835-20-8

PubChem ID

78243714

InChI Key

TZVJQEGKRLDTHQ-UHFFFAOYSA-N

SMILES

O=C(C2=CC=C(OCC(NC3CCN(CC4=CC=CC=C4)CC3)=O)C=C2)C1=CC=CC=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 46.5 100
Ethanol 4.65 10

Preparing Stock Solutions for AdipoRon hydrochloride

The following data is based on the product molecular weight 464.98.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.15 mL 10.75 mL 21.51 mL
5 mM 0.43 mL 2.15 mL 4.30 mL
10 mM 0.22 mL 1.08 mL 2.15 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Product Documents for AdipoRon hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AdipoRon hydrochloride

For research use only

Citations for AdipoRon hydrochloride

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