Catalog Number: 5175
Chemical Name: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
Biological Activity
Broad spectrum, irreversible inhibitor of serine proteases. Also inhibits NADPH oxidase activation in vitro. Attenuates airway inflammation in a mouse model of airway allergy.
Technical Data
  • M.Wt:
    239.69
  • Formula:
    C8H10FNO2S.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    30827-99-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds.
    Diatchuk et al.
    J.Biol.Chem., 1997;272:13292
  2. Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease.
    Saw et al.
    PLoS ONE, 2012;7:e41107

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