muscarinic receptor antagonist. Ki
values are 64, 417, 786, 211 and 5130 nM for human recombinant M2
muscarinic receptors, respectively.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold with the permission of Boehringer Ingelheim GmbH
Identification of the primary muscarinic autoreceptor subtype in rat striatum as M2 through a correlation of in vivo microdialysis and in vitro receptor binding data.
Billard et al.
Muscarinic receptor subtypes and smooth muscle function.
Eglen et al.
Muscarinic receptor subtypes in human bladder detrusor and mucosa, studied by radioligand binding and quantitative competitive RT-PCR: changes in ageing.
Mansfield et al.
Binding profile of a novel cardioselective muscarinic receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat.
Hammer et al.
Life Sci., 1986;38:1653
The citations listed below are publications that use Tocris products. Selected citations for AF-DX 116 include:
Showing Results 1 - 4 of 4